Evening Ebola Update, Sun, 12/7: 10th physician dies/GBV-C infection may improve survival   Leave a comment


Dear Colleagues:  Today is Sunday in the U.S; Sunday is the second day of rest in our Saturday/Sunday weekend.  EBOV reports from the news media and Web are decreased on the weekends.  But there is some news to report:

l. Al Jazeera reports that a 10th physician in Sierra Leone has died of EBOV.  Only 1 Sierra Leone physician with EBOV has survived his disease.

2.  Journal of Virology 3 December has an article by Lauck, et. al. from Pathology at the University of Wisconsin-Madison reporting that 13 of 49 patients with EBOV in Sierra Leone also had the pegivirus GBV-C.  These patients with GBV-C had a 50+% survival rate, while patients without GBV-C had a 20+% survival rate.  Patients between the ages of 21-45 years had the highest rate of GBV-C.  In HIV disease GBV-C decreases the pathogenicity of HIV by decreasing the immune response.  Perhaps GBV-C has the same action in EBOV.  Alternatively, the improved survival rate of EBOV patients with GBV-C may be due to their intermediate age (21-45 years).  See the article at: http://jvi.asm.org/content/early/2014/11/27/JVI.02752-14.full.pdf+html



Posted December 7, 2014 by levittrg in Ebola

Tagged with

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: