Evening Ebola Update, Mon, 12/8: EBOV survivors as trainers/Synthetic Ab against SUDV/Improve EPIC   Leave a comment

12/8/14

Dear Colleagues:

l.  WHO has begun to enroll EBOV survivors as ‘patient trainers’ for HCW about to care for infected EBOV patients.  These survivors can give HCW a true picture of what it is like to have EBOV at all stages of the infection.  Thus, when HCW encounter their first EBOV patients, the HCW are prepared for what they will face.  See the WHO article at: http://who.int/features/2014/ebola-patient-trainer/en/en

2.  Dr, Racaniello’s Microbe TV website today refers us to an article by Gang Chen, et. al. from the University of Toronto about a synthetic antibody built on a human scaffold that is effective against the Sudan strain of Ebola (SUDV) in mice.  This synthetic antibody was ‘built’ on the basis of the murine antibody 16F6.  The synthetic antibody has a human scaffold, not a murine antibody as 16F6 does.  There is no crossover activity against EBOV, but now we know that synthetic antibodies on a human framework can be devised against Ebola.  See the article at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201348/ 

3.  Fox News reports that the Dallas ER physician at Texas Health Presbyterian Hospital who saw Mr. Duncan on his initial visit to the ER did not see the note in the EMR that a fever was present.  The hospital uses the EPIC EMR system, but this was a human error, not a hardware error.  Perhaps the EPIC system can be revised to highlight in flashing letters when particular combinations of symptoms or signs are found in a patient; e.g., fever and travel to West Africa.  See the Fox News article at: http://www.foxnews.com/health/2014/12/08/dallas-ebola-patient-doctor-admits-missing-symptoms-in-initial-er-visit/

RGL, MD

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Posted December 9, 2014 by levittrg in Ebola

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