Evening Ebola Update, Sat, 1/17: Here are the ? vaccine trial coordinators need to ask before flying to Africa/Photo shows how difficult contact tracing can be/Malaria kills >850,000   Leave a comment


Dear Colleagues:

l.  Last night I posted an article by Lee, et. al. in The Lancet re: the several questions vaccine trial coordinators need to ask themselves before departing for West Africa with their vaccines for trials.  Tonight I list those seven questions:  Who will be vaccinated and who will decide who is vaccinated?  How will the vaccines reach the target population without becoming inactive?  How will the vaccines be administered and by whom?  How safe are the vaccines?  How will the benefits/risks of the vaccines be told to the population?  How will West African countries integrate the vaccine trials into their health programs?  What are the costs of the vaccines and who will pay the costs?  See Lee, et. al. discussion of each question at: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)62398-9/fulltext

2.  On 2 December the World Bank issued their report on the economic effects of the EBOV epidemic on Liberia, Guinea, and Sierra Leone.  For each country there were severe economic losses.  The few paragraph Summary can be found at the beginning of the ten page report at: http://www.worldbank.org/content/dam/Worldbank/document/Economic%20Impact%20Ebola%20Update%202%20Dec%202014.pdf  (The report does not allow me to copy and paste the Summary in this posting)

3.  Science 9 January has an article on how difficult it can be in Liberia to trace contacts.  The photo and the ‘map’ to the possible EBOV patient tell the whole picture of the contact tracers’ grueling trek to find the patient.  This article deals directly with Lee, et. al. question: How will the vaccines reach the target population without becoming inactive?  See the photo and map at: http://www.sciencemag.org/content/347/6218/120.full

4.  PLoS Speaking of Medicine lists world deaths due to parasitic diseases for 2014.  Malaria tops the list at > 850,000 deaths.  At least two other parasitic diseases are under-counted in the list according to the authors, Hotez, et. al.  See the list at: http://blogs.plos.org/speakingofmedicine/2015/01/16/one-million-deaths-parasites/



Posted January 18, 2015 by levittrg in Ebola

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