Evening Ebola Update, Mon, 1/26: WHO Exec. Board endorses Dr. Chan’s requests (where’s the $ coming from?)/GB-C infection reduces mortality in EBOV infection   Leave a comment

1/26/15

Dear Colleagues:

1.  NY Times reports that the WHO Executive Board endorsed yesterday a resolution containing Dr.Chan’s requests for ‘rapid response teams’ with full funding to respond to global health emergencies; a better mechanism to bring drugs and vaccines to market; and increased lab support in countries with global health emergencies.  See the NY Times article at: http://www.nytimes.com/2015/01/26/world/who-members-endorse-resolution-to-improve-response-to-health-emergencies.html?ref=health.  No details on where the funding for the ‘rapid response teams’ will come from.

2.  Journal of Virology February, 2015, has posted on-line an article by Lauck, et. al. from the University of Wisconsin and Harvard University/The Broad Institute re: the association of the pegivirus GB-C infection with EBOV infection in West African patients.  The presence of GB-C infection reduced the mortality of the EBOV infected patients, although the effect of increasing age was a confounding factor.  The presence of GB-C in HIV patients has previously been shown to reduce the mortality of HIV infection.  EBOV and GB-C infect myeloid and lymphatic immune cells respectively; the combination of both infections may mute the cytokine response to EBOV infection.  See: http://jvi.asm.org/content/89/4/2425.full?sid=dc9d3913-ad5c-4c54-96fd-b42d6aa88d3f

RGL, MD

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Posted January 27, 2015 by levittrg in Ebola

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