Evening Ebola Update, Wed, 2/18: Sierra Leone investigates ‘missing funds’; should do same for vaccine trials money/Using social media/Avoiding false findings   Leave a comment

2/18/15

Dear Colleagues:

l.  The Guardian reports that Sierra Leone has told EBOV fund administrators to report to the anti-corruption agency and explain why EBOV funds are ‘missing’ or ‘only partially documented’.  Since large amounts of money are involved also in clinical vaccine trials, Sierra Leone anti-corruption officials need to enforce documentation of how vaccine funds are spent as well.  See: http://www.theguardian.com/world/2015/feb/17/sierra-leone-investigates-alleged-misuse-of-emergency-ebola-funds

2.  PLoS Biology has highlighted an article published in 2013 by Bik, et. al. from the University of California at Davis Genome Center re: how scientists can use social media for gathering research and making public their research findings.  The article does not emphasize privacy and hacking issues as much as I would like to see.  See: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001535

3.  PLoS Medicine has highlighted an article published in 2005 by Ioannidis from Greece and Tufts University on why most published research findings are false.  Ioannidis’ C.V. contains many articles on the lack of power and bias of scientific articles.  The author says that research findings are often false due to: lack of power of the study (too few patients in the study populationd); innate bias; selective publishing of positive studies (while similar studies with negative results are not published).  One way to prevent false findings is to use large numbers of patients in a study or do meta-analysis of several studies.  See the article at: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124

RGL, MD

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Posted February 18, 2015 by levittrg in Ebola

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