Evening Ebola Update, 2/22: New RNA virus in Kansas/Nature issue on epigenetics/Fluorescence flow cytometry helps vaccine development   Leave a comment

2/22/15

Dear Colleagues:  Today is Sunday so my web sources are ‘quiet’.  I have posted two interesting and important articles re: a new virus and epigenetics respectively:

l.  CDC Emerging Infectious Disease May, 2015, has released a report by Kosoy, et. al. of CDC re: a novel RNA virus which has killed a Kansas man.  The virus is believed to have infected the man via a tick bite.  The filamentous form of the virus looks very much like EBOV (see Figure 1A in article cited).  See: http://wwwnc.cdc.gov/eid/article/21/5/15-0150_article

2.  Nature 19 February issue is devoted to an update on epigenetics.  The articles relate to: ‘Insights into three fundamental aspects of epigenetics: how the epigenome affects gene expression; how the epigenome changes during stem-cell differentiation… and how it changes during disease’.  See the lead Editorial at: http://www.nature.com/news/beyond-the-genome-1.16929

3.  This same issue of Nature has a Technology Feature ‘Measure for Measure’ about use of mass cytometry and fluorescence flow cytometry to identify proteins on immune cells which are attracted to specific antibodies.  This information can shorten the time to development of new vaccines.  See the article by Kling at: http://www.nature.com/nature/journal/v518/n7539/full/518439a.html

RGL, MD

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Posted February 22, 2015 by levittrg in Ebola

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